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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASTN2
All Species:
21.52
Human Site:
S245
Identified Species:
59.17
UniProt:
O75129
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75129
NP_054729.3
1339
148243
S245
R
I
P
Q
K
S
A
S
T
E
A
T
H
E
I
Chimpanzee
Pan troglodytes
XP_528403
1357
150757
S263
R
I
P
Q
K
S
A
S
T
E
A
T
H
E
I
Rhesus Macaque
Macaca mulatta
XP_001098403
1338
148255
S244
R
I
P
Q
K
S
A
S
T
E
A
T
H
E
I
Dog
Lupus familis
XP_538814
1187
132903
Q126
S
F
R
A
S
R
L
Q
A
H
N
S
V
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z10
1352
149372
S257
R
I
P
Q
K
S
A
S
T
E
A
T
H
E
I
Rat
Rattus norvegicus
XP_002726585
1354
149556
S259
R
I
P
Q
K
S
A
S
T
E
A
T
H
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515531
1305
145285
G221
Y
I
P
S
V
L
I
G
G
H
G
R
E
S
L
Chicken
Gallus gallus
XP_426626
1355
150279
S256
P
Q
P
Q
K
S
A
S
A
E
A
A
N
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660894
751
83839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99
86.2
N.A.
96.8
96.2
N.A.
47.3
47.5
N.A.
27.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
99.4
87.6
N.A.
97.8
97.7
N.A.
64.2
65.2
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
13.3
66.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
20
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
67
0
23
0
67
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
67
0
0
12
67
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
12
0
12
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
23
0
0
56
0
0
% H
% Ile:
0
67
0
0
0
0
12
0
0
0
0
0
0
12
67
% I
% Lys:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% N
% Pro:
12
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
67
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
56
0
12
0
0
12
0
0
0
0
0
12
0
0
0
% R
% Ser:
12
0
0
12
12
67
0
67
0
0
0
12
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
56
0
0
56
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _